How Getting a Great Sleep Helps You Make Healthy Choices

by Valerie Polley | Jan 17, 2019 | 0 comments

When you're tired, everything is more difficult, and that includes making good food choices. Sleep deprivation can interfere with your self control, appetite, metabolism, and cravings.

When you get enough sleep, it's easier to make good nutrition choices. You have more self control, and sleep helps keep hunger hormones regulated. You're less likely to crave foods that may not be a good nutrition choice.

Sleep Deprivation and Hormones
Insufficient sleep can interfere with the regulation of hormones that affect your metabolism and appetite. These hormones include ghrelin, leptin, cortisol, and insulin.

When you're sleep deprived, your ghrelin production increases, which tells your brain your hungry, even if that isn't necessarily the case. At the same time, your leptin production decreases. This hormone tells your brain that it's full. A lack of sleep can artificially increase your appetite, as these hormones signal to your brain that you're hungry and not full.

Sleep deprivation can also interfere with proper metabolism of carbohydrates, which can lead to increased production of cortisol, a stress hormone, and insulin. When your body grows resistance to insulin, it becomes more difficult to process fat and sugars and your body stores more of it as fat, which can lead to weight gain.

Sleep Deprivation and Self Control
When you're sleep deprived, your self control suffers. It's difficult to stick to a healthy diet, and you are more prone to seeking out junk food. People who are sleep deprived are more likely to consume more calories and more carbohydrates overall while drinking less water.

Your cravings may change when you're sleep deprived, causing you to crave foods that are rich in fat or carbohydrates. You may make poor snack choices at night and eat bigger portions.

Sleep deprivation increases fatigue. That makes it more difficult for you to say no to poor food choices, and you have less energy to live a healthy lifestyle including exercise.

Tips for Improving Sleep
With more restful sleep, you're in a better position to make good food choices. Use these tips to improve your sleep at night.

Create a healthy sleep environment. Where you sleep is almost as important as how much you sleep. A healthy sleep environment can help you relax and get the rest you need, while an unhealthy one can leave you feeling anxious and restless at night. Your bedroom should be calm, dark, cool, comfortable, and quiet. Especially important is a mattress that appropriately meets your needs and offers support and pain relief.

Practice good sleep hygiene. Good sleep habits can help improve the quality of your sleep. Maintain a regular bedtime and wake up at the same time each day. Create a consistent bedtime routine, so you're signaling to your brain that it's time to go to sleep each night when you go through your same actions before bed, such as brushing your teeth and reading a book.

Consider how food may affect your sleep quality. Consuming caffeine, chocolate, sugar, or alcohol can interfere with your ability to sleep well. Heavy meals just before bed can make it difficult for you to sleep as your body digests your food. It's best to avoid these foods in the hours before bed.

Selina Hall is an expert on sleep health and wellness for BestMattressReviews.com. She believes that sleep is one of the most important pillars of health. Selina lives in Portland, Oregon. She sleeps best under a handmade quilt passed down from her great-grandmother.

Our gut microbiome (the community of trillions of microbes that live in our gut) plays a key role in maintaining metabolic and immune health. Gut dysbiosis occurs when the composition and diversity of our gut microbiome shift. This could include overgrowth of harmful bacteria or a decrease in beneficial bacteria. Gut dysbiosis has been linked to a wide range of negative health outcomes, including increased levels of inflammation and changes in metabolism.

Many people switch to non-nutritive sweeteners like sucralose, aspartame, and stevia for health reasons, and for decades, we've believed that they pass through our bodies without affecting us. But emerging research shows that these compounds interact directly with our gut microbiome and may have potential negative effects on our health. 

This article will review what we currently know about the relationship between non-nutritive sweeteners (including artificial sweeteners and calorie-free natural sweeteners) and the gut microbiome, plus practical advice for navigating sweeteners.

Sucralose

Sucralose (Splenda) is an artificial sweetener commonly used in baked goods, gums, and sugar-free beverages and is approximately 600 times sweeter than sucrose (table sugar). However, recent research has linked it to adverse health effects such as systemic inflammation, metabolic disease, and gut dysbiosis. For example, a 2022 study found that sucralose consumption increased harmful bacteria and reduced beneficial bacteria, which was associated with changes in insulin and glucose levels.

Additionally, a 2025 randomized controlled trial examining the effects of replacing added sugars with sucralose found that people with type 2 diabetes who consumed sucralose experienced reductions in both alpha diversity (the number and types of species present in a single person) and beta diversity (differences in microbial composition between people). Interestingly, the people with overweight and obesity without type 2 diabetes did not experience the same changes.

Overall, animal studies and limited human studies suggest that sucralose may trigger intestinal inflammation, likely through its effects on the gut microbiome. However, since most of the evidence we have comes from test tube or animal studies, these results should be interpreted cautiously.

Aspartame

Aspartame is another commonly used artificial sweetener that is about 200 times as sweet as sucrose. While it does contain some calories, because you don't need much of it to reach the same sweetness levels as sucrose, these calories are negligible.

Like sucralose, most of the research into the gut effects of aspartame has been done in animals. However, we do have some very small human studies. A 2022 randomized controlled trial (RCT) involving 20 healthy adults found that participants taking aspartame showed changes in both probiotic (beneficial) and pathogenic (harmful) bacteria, but the changes were specific to each individual. 

Why the differences? It's likely due to the "responder vs. non-responder" phenomenon. We all have differences in our "baseline" microbiome. While certain bacterial species are common in healthy populations, our microbiome is as unique as a fingerprint. Whether an artificial sweetener has positive or negative effects on our microbiome may depend on which species are already present in our gut, as well as on our habitual diet. This difference in responses makes it very challenging to draw firm conclusions about whether artificial sweeteners are harmful.

Stevia

Many people choose stevia because it's a "natural" zero-calorie sweetener. Studies have shown mixed results regarding the effects of stevia on the gut microbiome. For example, while some in vitro (test tube) and in vivo (animal) studies have reported potentially harmful effects of stevia on the gut microbiome, others have found no impact, and some even reported beneficial effects through inhibition of inflammatory pathways.

Additionally, a 2024 human study found that stevia had no significant effect on the gut microbiome. This highlights the importance of not forming conclusions based solely on test tube and animal studies. Overall, it appears that stevia is a potentially less-harmful alternative to artificial sweeteners like sucralose and aspartame.

Practical Advice for Navigating Sweeteners

Since the research on artificial sweeteners is still evolving, the decision to include or avoid them comes down to personal preference. Here are some tips for including them in your diet in moderation:

  • Try gradually reducing the amount you use: If you typically use two packets of sweetener in your coffee or tea, try gradually reducing to one packet. Our taste buds are highly adaptable, and you may find that one packet is sweet enough once you get used to it.
  • Check your labels: Low- or no-calorie sweeteners (such as sucralose, aspartame, and sugar alcohols like erythritol) are often hidden in low-sugar foods like protein bars, yogurt, and diet sodas. Awareness is the first step to reducing your intake.
  • Rotate your sources: If you do use artificial sweeteners, try switching up the types you use. Since different sweeteners may affect your gut microbiome in different ways, this may reduce the concentrated impact on your gut.
  • Switch to stevia: While animal and test-tube studies show mixed findings, human research indicates that stevia has a limited effect on the gut microbiome, making it a better choice for people seeking to support their gut health.

Another way to support your gut if you regularly use artificial sweeteners is to rebuild gut diversity with fiber and fermented foods, while focusing on whole-food sweeteners.

  • High fiber prebiotic foods (like legumes, whole grains, garlic, onions, asparagus, and under-ripe bananas) act as "fuel" for your healthy gut microbes. Aim to include a variety of these foods in your diet to support the microbes already in your gut.
  • Add fermented foods, like unpasteurized sauerkraut and kimchi, kefir, or kombucha, to your diet. Some fermented foods contain live, beneficial bacterial cultures, while others are rich in "postbiotics" (beneficial compounds like short-chain fatty acids, which are produced when bacteria break down prebiotics).
  • Try using whole-food sweeteners instead of artificial ones. For example, sweeten plain yogurt with vanilla extract and berries or add dates to smoothies or homemade energy bites.

Final Thoughts

Emerging research suggests that certain low- or no-calorie sweeteners, including sucralose and aspartame, may affect the gut microbiome, whereas stevia appears to have a less negative effect. While individual responses can vary with a person's unique baseline microbiome, certain artificial sweeteners may increase inflammation or reduce gut microbiome diversity.

If you need personalized support navigating sweeteners or supporting your gut health, Blue Tree Nutrition can help. Click here to get in touch!

 

 

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Hello, I am

Valerie

My name is Valerie Polley. I am a Indianapolis-based registered dietitian and owner of Blue Tree Nutrition. I consult with clients both local and far away.
I have a bachelor’s degree in nutrition from Purdue University and I have been practicing for 20 years.
I thoroughly enjoy helping clients through their gut health journey. I see a range of GI issues including, but not limited to celiac disease, IBS and SIBO. I also specialize in the FODMAP elimination diet.